Salmon DNA in Skincare? The Science Behind PDRN and Skin Regeneration

Jul 30

At HollaceMD Advanced Laser + Aesthetics, we combine cutting-edge science with advanced aesthetic treatments to deliver real skin transformation.

A New Era of Healing and Rejuvenation—Backed by Science, Not Hype

What Is PDRN?

It might sound surprising, but salmon DNA—specifically from rainbow trout (Oncorhynchus mykiss) and Chum salmon (Oncorhynchus keta)—is making waves in skincare. The key ingredient? PDRN (Polydeoxyribonucleotide), a highly purified DNA compound that supports your skin’s natural repair and regeneration processes.

Clinically used in wound healing and anti-aging medicine, PDRN is safe, biocompatible, and approved for use in many countries.

At HollaceMD Advanced Laser + Aesthetics, every Genius RF Microneedling treatment includes a topical PDRN application—valued at $175—plus a 7-day post-care regimen from FactorFive, valued at $80, at no extra cost.

Why? Because science shows that your skin heals and performs better when supported with the right ingredients at the right time.

⚙️ How Does PDRN Work?

1. Cell Repair Activation

PDRN stimulates specific A2A receptors in the skin to:

Boost collagen and elastin production
Improve blood circulation
Speed up post-treatment healing

2. DNA Repair & Cell Turnover

Nucleotides—the building blocks of DNA—are essential for skin regeneration. PDRN delivers them directly, helping to:

Repair damaged skin cells
Accelerate healing after treatments like RF microneedling or lasers

3. Soothing Anti-Inflammatory Effects

PDRN reduces inflammation without suppressing your immune system—ideal after procedures that may cause irritation or redness.

4. Collagen & Elasticity Boost

Studies confirm PDRN enhances collagen density and skin elasticity, creating firmer, smoother, and more youthful skin.

📊 Where Is PDRN Used?

PDRN is clinically proven and widely used in:

Wound Healing – Reduces healing time and minimizes scars
Dermatology – Treats conditions like rosacea, eczema, and chronic inflammation
Aesthetic Medicine – Improves hydration, fine lines, and skin texture
Microscopic Studies – Reveal stronger collagen structures and thicker skin

🐟 Why Salmon DNA?

Salmon DNA is remarkably similar to human DNA, making it a safe and effective option for skin therapy. It’s:

Naturally rich in healing nucleotides
Refined to medical-grade purity
Gentle and low risk for irritation

💼 When to Use PDRN in Aesthetics

PDRN works best when your skin is already in “repair mode,” such as after:

RF Microneedling (Genius RF)
Laser Resurfacing

Benefits include:

Faster recovery
Reduced redness
Improved long-term results
Enhanced collagen remodeling

🔗 Best Paired With: Genius RF Microneedling

Genius RF targets deeper layers of the skin to boost collagen from within. When paired with PDRN, it amplifies both immediate and long-term results.

📍 Bottom Line

PDRN isn’t just a skincare buzzword—it’s a scientifically backed ingredient with powerful healing and anti-aging benefits. Whether you’re post-procedure or looking to optimize your skin's resilience, this DNA-based treatment supports renewal from the inside out.

Combine it with Genius RF Microneedling for your most effective skin transformation yet.

➡ Click to learn more and book a consultation

Dori Cazorla